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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS2
All Species:
18.48
Human Site:
S425
Identified Species:
29.05
UniProt:
Q9NRM7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRM7
NP_055387.2
1088
120136
S425
P
P
G
K
A
E
P
S
L
P
A
P
N
T
V
Chimpanzee
Pan troglodytes
XP_001149147
1088
120220
S425
P
P
G
K
A
E
P
S
L
P
A
P
N
T
V
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
R239
Q
S
L
L
T
P
S
R
N
S
L
N
V
D
L
Dog
Lupus familis
XP_534537
1097
121903
S439
V
P
S
K
T
E
P
S
M
P
S
P
N
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSJ6
1042
115454
T403
L
P
A
P
N
T
V
T
A
V
T
A
A
H
I
Rat
Rattus norvegicus
NP_001100737
1042
115346
T402
L
P
A
P
N
T
V
T
A
V
T
A
A
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
S470
R
A
S
H
P
A
S
S
Q
P
S
A
T
T
V
Chicken
Gallus gallus
XP_417143
1127
126652
S464
P
P
G
K
P
D
P
S
I
T
S
P
N
T
I
Frog
Xenopus laevis
NP_001087838
1118
125984
A472
W
Q
V
L
S
N
N
A
Q
T
S
A
T
T
V
Zebra Danio
Brachydanio rerio
NP_001121728
1078
119704
S410
V
A
G
K
P
E
S
S
L
G
P
P
N
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NBK5
463
53314
Honey Bee
Apis mellifera
XP_395146
1137
124999
V523
Q
R
G
M
H
H
P
V
P
P
P
P
Y
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
A563
P
P
P
P
Y
R
P
A
A
P
V
Q
S
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
K186
S
S
G
L
R
S
V
K
S
F
Q
R
L
Q
Q
Red Bread Mold
Neurospora crassa
P38679
598
67999
T28
N
D
R
T
Y
P
T
T
P
S
T
F
P
Q
P
Conservation
Percent
Protein Identity:
100
99.4
70.5
86.6
N.A.
82.5
82.9
N.A.
48.7
75.6
47.8
63.5
N.A.
22.5
40.8
N.A.
38.6
Protein Similarity:
100
99.7
71.2
89.8
N.A.
86.5
86.9
N.A.
61
83.2
58.7
72.9
N.A.
31.4
52.7
N.A.
52
P-Site Identity:
100
100
0
60
N.A.
6.6
6.6
N.A.
26.6
60
13.3
53.3
N.A.
0
26.6
N.A.
26.6
P-Site Similarity:
100
100
6.6
80
N.A.
20
20
N.A.
33.3
86.6
33.3
60
N.A.
0
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.1
24.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
36.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
14
0
14
7
0
14
20
0
14
27
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
7
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
0
27
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% F
% Gly:
0
0
40
0
0
0
0
0
0
7
0
0
0
7
0
% G
% His:
0
0
0
7
7
7
0
0
0
0
0
0
0
14
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
34
% I
% Lys:
0
0
0
34
0
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
14
0
7
20
0
0
0
0
20
0
7
0
7
0
7
% L
% Met:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
14
7
7
0
7
0
0
7
34
0
0
% N
% Pro:
27
47
7
20
20
14
40
0
14
40
14
40
7
0
7
% P
% Gln:
14
7
0
0
0
0
0
0
14
0
7
7
0
14
7
% Q
% Arg:
7
7
7
0
7
7
0
7
0
0
0
7
0
0
0
% R
% Ser:
7
14
14
0
7
7
20
40
7
14
27
0
7
0
0
% S
% Thr:
0
0
0
7
14
14
7
20
0
14
20
0
14
47
7
% T
% Val:
14
0
7
0
0
0
20
7
0
14
7
0
7
7
27
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
14
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _